Encoding of auditory information in auditory; effects of general anesthetics
Michele Basso (Steering Committee Member)
Neural basis of cognition
The role of the cytoskeleton in axon outgrowth and guidance
Regulation of neuronal differentiation and neurotransmitter phenotype
Regulation of axon guidance by second messengers
Computational neuroscience in sensory systems
Genetic engineering for Alzheimer's Disease and Parkinson's Disease; amyotrophic lateral sclerosis and Huntington's Disease.
Cellular mechanisms underlying respiratory rhythm generation and plasticity
Kinetics of GABA binding and GABAA receptor gating; neural information encoding.
Nonhuman primate models; regulation of food intake and energy expenditure; aging
Sensory and learning processes of speech perception
Neuroproteomics; biological mass spectrometry
Psychobiological processes affecting behavioral self-regulation and pathological dysregulation
Functional magnetic resonance imaging and transcranial magnetic stimulation to study cognition.
Biology of neural stem cells: fate choices in vitro and repair following transplantation
Neural modulation of visual signals in the thalamus; photosensitive epilepsy
Peter Van Kan (Steering Committee Member)
Neural control of reaching to grasp in awake behaving primates
Sensorimotor transformations in the mammalian central nervous system.
Embryonic stem cells; neural differentiation
MRI techniques to study brain structure in children with developmental disabilities; physico-mathematical models of brain dynamics.
Studies of brain function in patients with cognitive disorders
Michael R. Koenigs
Human lesion studies; emotion, decision-making, and social behavior.
Paul L. Kaufman
Primate ocular accommodation; ocular fluid drainage; optic neuropathy
Determining cataract, macular degeneration, diabetic retinopathy, optic nerve problems from images
Molecular biology of normal and tumor-derived neural stem cells
Binaural hearing and speech
Neurological endovascular surgery/interventional neuroradiology
Hippocampal oscillations and memory; studies of gene-targeted animals
Joanne Robbins (Steering Committee Member)
Enhancing function of the bulbar innervated musculature with particular interest in swallowing and speech outcomes.
Epilepsy and EEG signal analysis.
Neurostimulation systems for movement disorders, pain, and epilepsy; neurosurgical navigation and neuroimaging; endovascular approaches for functional neurosurgery
Molecular mechanisms underlying ischemic brain damage
Neural basis of consciousness; functions of sleep
Human brain mapping in normal and patient patient populations
PHYSICAL SCIENCE AND ENGINEERING
Diagnostic, functional, and interventional MRI neuroimaging methodology
Developing and translating novel positron emission tomography (PET) methodologies
Animal models of neuorolical disorders for clinical translation
Aaron S. Field
Quantitative MR imaging of myelin disease and repair in the CNS
Pictures, video, visualizations, animation, and virtual environments
Kristyn S. Masters
Synthesis of bioactive materials that direct cell function, characterization of cell-material interactions, tissue engineering, drug delivery
Beth Meyerand (Co-director, Principal Investigator)
Magnetic Resonance Imaging methods to aid in the understanding of brain function in different disease states.
Tissue engineering, drug delivery and gene therapy
Robert Radwin (Steering Committee Member)
Quantification of human performance; design of human-machine interfaces for functional augmentation and rehabilitation.
Role of astrocytes, neurons and neural stem cells in formation and maintenance of the blood-brain barrier and consequences for brain drug delivery
Biomechanics; motor control; locomotion
Ultrasound elastography or strain imaging for detecting and classifying vulnerable plaque
Barry Van Veen
Statistical signal processing algorithm development and analysis
Justin Williams (Co-director, Principal Investigator)
Engineering interfaces with the nervous system for diagnosis, discovery and treatment of neurological disease and disorders.